The serotonin agonist is the compound known for its enhancing and the activating capabilities regarding the serotonin receptor cells that is present in your brain. This acts as a neurotransmitter and is in collaboration with the creation of positive moods and relaxation.
Adequate levels of the same help to protect you against the conditions of depression but during the low level phase you will discover yourself growing moodier becoming more anxious and irritable. Additional symptoms like headaches may also accompany.
Agonists are used in situations marked by theelongated serotonin deficiency which leads to mood disorders and other related symptoms.
Works
- During the normal conditions serotonin is secreted into your central and peripheral nervous system where it develops as the chemical messenger by the act of binding to specific receptors.
- Serotonin is involved in activating the receptors on serotonergic cells or neurons in your brain.
- Agonists works to improve certain receptors
They commonly work as a supplement or drugs that combines with the serotonergic receptors leading to the production of the physiological response .The body produces nearly a dozen serotonin receptor agonists all these are efficient in enhancing the activation procedure of your serotonergic system.There are also a numerous drugs and natural supplements available in the market that also perform the same function. Some of the main types of agonists are listed below:
- 5-HT 1A agonists which are found in many SSRIs andare used in antidepressants.
- 5-HT 1B and 5-HT 1D agonistsare those that are found in sumatriptan, and are used for treating migrainesissues .
- 5-HT 2C agonists are synonymous to the weight loss drugs .
Mechanism of function
They combine with specific receptor to work in the specific pathways. Depending on the agonist being employed different components of the serotonergic system is being activated. This allows to bring about an array of certain neural functions.
Such as the weight loss drugs work by using the agonists that trigger the serotonin receptors involved in controlling appetite. Anti-depressant drugs like many SSRIs work selectively to activate brain circuits that are involved in mood enhancing . Lastly serotonin agonist drugs that are used for migraines and headaches are designed to work by the combination of the receptors that relevant to those pathways.
Among these many found and market available SSRIs the most frequently prescribed with over a 40 million Americans using it throughout the past 3 decades is the above mentioned types . Selective serotonin reuptake inhibitors (SSRIs) falls under a class of prescribed drugs that do not allow this neurotransmitter from being absorbed back into your nervous system majorly made by the neurons once it is involved in the process of being released.
SSRIs work by increasing the movement of serotonin to receptor cells this there by enhances the stimulation of these receptors that you have known about through the article . While SSRIs are considered safe for most when used under the doctor’ssupervision there can be side effects such as the changes in mood, libido and weight gain when used for a long span of time.
